Mutations in Single Gene Underlie Vulnerability to Two Unrelated Types of Infections

When a genetic error weakens a child’s immunity, otherwise nonthreatening microbes can sicken and sometimes kill. In work published July 9 in Science, researchers at The Rockefeller University and their colleagues identify one surprising case in which mutations in a single gene render children vulnerable to two very different diseases: aggravating, but treatable fungal infections, as well as invasive and potentially fatal bacterial disease.

Website: https://www.arjonline.org/biosciences/american-research-journal-of-biosciences/